IVF with a donor's eggs and sperm of the male partner

Visit by Patients for Medical Examination

Both the male and female partner visits the clinic for a thorough medical examination and blood tests. They also consult with an embryologist. Using the test results, the fertility specialist determines which IVF programme is most appropriate for the couple and explains the treatment process in detail.

Selection of Egg Donor

The couple is provided a donor profiling format.

Stimulation

The selected donor will be monitored through blood investigations and an ultrasound on day two or three of the menstrual cycle. Based on the results, the ovaries are stimulated with medication to promote the growth of follicles containing the eggs; this can last for eight to 12 days. The response of ovaries (quantity & quality of follicle recruited) is monitored through ultrasounds and blood investigations at regular intervals. During this treatment the recipient also undergoes hormonal treatment

Egg Collection

After eight to 12 days of taking the medicine, an injection (trigger) is administered to assist with final maturation of the egg and loosening of the egg from the follicular wall. The egg donor then visits the clinic for the egg retrieval process, which will be performed 34 to 36 hours after the trigger administration. Egg retrieval is a day care procedure that is performed with ultrasound guidance under sedation to make it painless. The eggs are then retrieved and processed by embryologist.

Sperm Collection

On the same day, the male partner provides a fresh semen sample. If needed, sperm can be extracted from a testicle or epididymis in a separate procedure.

Fertilisation

Different procedures can be used to fertilise the collected eggs. In this step, the sperm that were processed in the previous step are used to fertilise the donated eggs. Each mature egg receives a single healthy sperm. Sixteen to 18 hours after the eggs receive the sperm; they are checked to see if fertilisation has taken place. An egg that is fertilised is referred to as an embryo; the embryo is then cultured in an incubator for several days.

Embryo Transfer

Based on the quantity, quality and growth of cultured embryos, the embryologist selects the best embryo and an appropriate day for transfer into the uterus of the female partner

After Transfer

After the embryo transfer, specialists may prescribe medicines which enhance the chances of embryo implantation. After the stipulated period of time, pregnancy tests are conducted to confirm pregnancy.