IVF with the eggs of the female partner and sperm of the male partner
Visit by Patients for Medical Examination
Both the male and female partner visits the clinic for a thorough medical examination and blood tests. They also consult with an embryologist. Using the test results, the fertility specialist determines which IVF programme is most appropriate for the couple and explains the treatment process in detail.
The female partner needs to visit on day two or three of her menstrual cycle, when hormonal investigations are done along with an ultrasound. The ovaries are stimulated with medication to promote the growth of follicles containing the eggs; this process can last for eight to 12 days. The response of the ovaries (quantity and quality of follicles recruited) is monitored through ultrasounds and blood investigations at regular intervals.
After eight to 12 days of taking the medicine, an injection (trigger) is given to assist with the final maturation of the egg and loosening of the egg from the follicular wall. The patient must visit the clinic for the egg retrieval process, which takes place 34 to 36 hours after the trigger is given. The retrieval process is a day care procedure that is performed with ultrasound guidance under sedation. Once retrieved, the eggs are processed by an embryologist in the laboratory.
On the same day, the male partner provides a fresh semen sample, which is analysed and processed by an embryologist. If required, sperm can be extracted from a testicle or epididymis in a separate procedure.
Different procedures can be used to fertilise the collected eggs. In this step, the sperm that were processed in the previous step are used to fertilise the eggs. Each mature egg receives a single healthy sperm. Sixteen to 18 hours after the eggs receive the sperm; they are checked to see if fertilisation has taken place. An egg that is fertilised is referred to as an embryo; the embryo is then cultured in an incubator for several days.
Based on the quantity, quality and growth of cultured embryos, the embryologist selects the best embryo and an appropriate day for transfer into the uterus of the female partner.
After the embryo transfer, specialists may prescribe medicines to enhance the chances of embryo implantation. After the stipulated period of time, pregnancy tests are conducted to confirm pregnancy.